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'É'(ü(D)�)%+z+) ¬­®þÿ£¤¥Ü	"#a‹ëìía!X“Èò,DR�" ''é'ê'ø'ù'q+r+s+x+y+  7š  qGACNNNNNNGTC,CCAGGCCTGG,GATCCGGATC,CCWGGTACCWGG,CCANNNNNTGG,CCAGGNNNTGG,CCANNNCCTGG,CCAGGNCCTGG,GCACNNNAACGTTNNNGTGC,CACNNNGTG,CCNNNNNNNGG,AACNAACRYGTGCGTGC,GCACGCACRYGTTNGTT,GCACNAACRYGTTNGTGC,AACGCACRYGTGCGTT,GACNNNNNGTC,GAANNNNNNNTTGG,CCAANNNNNNNTTC,CACNNNNGTG,AACACNNNNGTGC,GCACNNNNGTGTT,GCANNNNNNTGC,GAACNNNNNNTCC,GGANNNNNNGTTC,CAGNNNCTG,CCAGGNNCTG,CAGNNCCTGG,CCWGGGCCC,GGGCCCWGG,CCWGGGCCCWGG,AACNNNNNNGTGCACNNNNNNGTT,GACNNNGTC,GAANNNNTTC,CCWGGTACC,GGTACCWGG,CCWGGWCCWGG,ACNNNNGTAYC,GRTACNNNNGT,CCWGGYRCCWGG,GAAGNNNNNNTAC,GTANNNNNNCTTC,AACGGCNNNGTGC,GCACNNNGCCGTT,GCACGGCNNNGTT,AACNNNGCCGTGC,CGANNNNNNTGC,GCANNNNNNTCG,CGATCNNNNTGC,GCANNNNGATCG,TGANNNNNNTCA,TGATCNNNNTCA,TGANNNNGATCA,TGATCNNGATCA,AACCTGCNNGTGC,GCACNNGCAGGTT,GCACCTGCNNGTT,AACNNGCAGGTGC,GCCNNNNNGGC,AACNNNNNNGTGCMC,GKGCACNNNNNNGTT,CCWGGNCCWGG,AACTGGGNNGTGC,GCACNNCCCAGTT,GCACTGGGNNGTT,AACNNCCCAGTGC,GACNNNNGTC,GAGNNNNNCTC,CCWGGTCTC,GAGACCWGG,GATNNNNATC,GATCNNNATC,GATNNNGATC,GATCNNGATC,CCWGGCGCCWGG,ACNNNNNCTCC,GGAGNNNNNGT,AACNNNNNNGTGCAG,CTGCACNNNNNNGTT,GATCATGATC,CCWGGNNCCWGG,AACTGGNNNGTGC,GCACNNNCCAGTT,GCACTGGNNNGTT,AACNNNCCAGTGC,AACNAACCGGTGCGTGC,GCACGCACCGGTTNGTT,GCACNAACCGGTTNGTGC,AACGCACCGGTGCGTT,GCANNNNNTGC,GCACNNNNNNGTTCGAACNNNNNNGTGC,CCTNNNNNAGG,GCNNNNNNNGC,CCANNNNNNTGG,CCAGGNNCCTGG,CCTGGCCAGG,CAANNNNNGTGG,CCACNNNNNTTG,TTTAAACNNNNNNGTGC,GCACNNNNNNGTTTAAA,GCACNNNNNNGTTTAAACNNNNNNGTGC,CCAGGNCCY,RGGNCCTGG,CCWGGGNCCTGG,CCAGGNCCCWGG,AAGNNNNNCTT,GAYNNNNNVTC,GABNNNNNRTC,GAYNNNNNRTC,GATCNNNNVTC,GABNNNNGATC,GAYNNNNGATC,GATCNNNNRTC,GATCNNNGATC,GTYAACNNNNNNGTGC,GCACNNNNNNGTTRAC,GCACNNNNNNGTTAACNNNNNNGTGC,GATCNGATC,TAACTATAACGGTCCTAAGGTAGCGA,TCGCTACCTTAGGACCGTTATAGTTA,CTCTCTTAAGGTAGC,GCTACCTTAAGAGAG,TAGGGATAACAGGGTAAT,ATTACCCTGTTATCCCTA,GTTAACNNNNNNGTGC,GCACNNNNNNGTTAAC,AACNAACGCGTGCGTGC,GCACGCACGCGTTNGTT,GCACNAACGCGTTNGTGC,AACGCACGCGTGCGTT,TCCAACNNNNNNGTGC,GCACNNNNNNGTTGGA,CAYNNNNRTG,AACAYNNNNGTGC,GCACNNNNRTGTT,GTTTAAACNNNNNNGTGC,GCACNNNNNNGTTTAAAC,CCWGGCGCC,GGCGCCWGG,CCWGGNNCC,GGNNCCWGG,GATCGCGATC,AACNAACATGTGCGTGC,GCACGCACATGTTNGTT,GCACNAACATGTTNGTGC,AACGCACATGTGCGTT,TGGCAAACAGCTATTATGGGTATTATGGGT,ACCCATAATACCCATAATAGCTGTTTGCCA,ATCTATGTCGGGTGCGGAGAAAGAGGTAATGAAATGG,CCATTTCATTACCTCTTTCTCCGCACCCGACATAGAT,AACNNGCACGTGCNNGTT,GAACNNNNNCTC,GAGNNNNNGTTC,CCAGGWCCY,RGGWCCTGG,CCWGGGWCCTGG,CCAGGWCCCWGG,CCAGGWCCTGG,TTATAACNNNNNNGTGC,GCACNNNNNNGTTATAA,GCACNNNNNNGTTATAACNNNNNNGTGC,GAACNNNNNNTAC,GTANNNNNNGTTC,GGCCNNNNNGGCC,AACNNACTAGTGC,GCACTAGTNNGTT,AACTAGTNNGTGC,GCACNNACTAGTT,AACNAACTAGTGCGTGC,GCACGCACTAGTTNGTT,GCACNAACTAGTTNGTGC,AACGCACTAGTGCGTT,AACNNNAACGTGCNNGTGC,GCACNNGCACGTTNNNGTT,GCACCCANNNGTT,AACNNNTGGGTGC,TTAACNNNNNNGTGC,GCACNNNNNNGTTAA,CACNNNNNNTCC,GGANNNNNNGTG,CACNNNNGATCC,GGATCNNNNGTG,GATCTAGATC,CCANNNNNNNNNTGG,CCAGGCCT,AGGCCTGG,CCTCGAGG,GATCCGGA,TCCGGATC,GGCGCGCC,GCGATCGC,CCWGGWCC,GGWCCWGG,GATCGATC,GATCATGA,TCATGATC,GCGGCCGC,CCTGGCCR,YGGCCAGG,CCWGGNCC,GGNCCWGG,GGCCGGCC,RTGCGCAY,GATCNNGA,TCNNGATC,CGCGCGCG,CCTGGCCA,TGGCCAGG,CGCCGGCG,GTTTAAAC,GATCGCGA,TCGCGATC,TTAATTAA,VCTCGAGB,CCTGCAGG,CRCCGGYG,CGTCGACG,ATTTAAAT,GCCCGGGC,GATCTAGA,TCTAGATC,CACCTGC,GCAGGTG,CCTNAGG,GATCGAT,ATCGATC,CCTCAGC,GCTGAGG,GCTNAGC,CCTNAGC,GCTNAGG,GCTCTTC,GAAGAGC,GGTNACC,CGGWCCG,ACCWGGT,RGGNCCY,CCTGGAG,CTCCAGG,GGTGATC,GATCACC,GATCNGA,TCNGATC,GGGWCCC,GAAGATC,GATCTTC,CCCWGGG,TCCNGGA,TCCWGGA,RGGWCCY,TTATAA,AGGCCT,GACGTC,GTMKAC,TCCGGA,TGCGCA,ACCTGC,GCAGGT,GGTACC,AGTACT,GGYRCC,CCGCTC,GAGCGG,AACGTT,YGGCCR,RAATTY,CTGAAG,CTTCAG,CACGTG,GRCGYC,AGCGCT,CTTAAG,ACRYGT,ACCGGT,ACTAGT,CACGTC,GACGTG,GWGCWC,GTGCAC,CYCGRG,GGGCCC,ATTAAT,CCTAGG,TTCGAA,GCTAGC,GKGCMC,TGGCCA,GGATCC,GRGCYC,ATCGAT,CACGAG,CTCGTG,GGCGCC,GAAGAC,GTCTTC,GCATGC,GTATCC,GGATAC,TGATCA,ACTGGG,CCCAGT,CTRYAG,RGCGCY,AGATCT,GGNNCC,CTGGAG,CTCCAG,CTTGAG,CTCAAG,CGATCG,GGTCTC,GAGACC,YACGTR,CCNNGG,GAATGC,GCATTC,WCCGGW,GCAATG,CATTGC,RCCGGY,GCGCGC,GAGGAG,CTCCTC,CGGCCG,CCCAGC,GCTGGG,GTGCAG,CTGCAC,CGRYCG,CGTACG,CGTCTC,GAGACG,CCATGG,TCGCGA,GDGCHC,TGTACA,TCATGA,ACATGT,GTATAC,CCWWGG,CTCTTC,GAAGAG,GCNNGC,CCRYGG,GTTAAC,RCATGY,TACGTA,RGATCY,GCGATG,CATCGC,GCAGTG,CACTGC,CCCGGG,CCGCGG,TTTAAA,GGCGGA,TCCGCC,GAGCTC,GATATC,CTGRAG,CTYCAG,CAGCAG,CTGCTG,GAATTC,ATGCAT,CATATG,GTYRAC,AAGCTT,GTNNAC,TCNNGA,CAATTG,ACGCGT,TCCRAC,GTYGGA,GCCGGC,CMGCKG,GCCGAG,CTCGGC,CTCGAG,CTGCAG,CAGCTG,GTCGAC,CTYRAG,AATATT,GATCGA,TCGATC,GACCGA,CACCCA,TCGGTC,TGGGTG,WGTACW,TARCCA,TGGYTA,TCTAGA,GGATC,GATCC,CCWGG,GTCTC,GAGAC,GCWGC,GGNCC,CCSGG,GGTGA,TCACC,GGWCC,GCAGC,GCTGC,CCATC,GATGG,ACGGC,GCCGT,GCNGC,CCNGG,GCATC,GATGC,ACTGG,CCAGT,GGATG,CATCC,CTCAG,CTGAG,GGGAC,GTCCC,ACNGT,CTNAG,CAGTG,CACTG,GACGC,GCGTC,CCCGC,GCGGG,GANTC,CGWCG,TCNGA,CCTTC,GAAGG,GTNAC,GAAGA,TCTTC,GAGTC,GACTC,GTSAC,GAWTC,GCSGC,CASTG,ATGAA,TTCAT,ACGGA,TCCGT,CGCG,CCGC,GCGG,GTAC,AGCT,GCGC,CTAG,GATC,GGCC,CCGG,CATG,RGCY,YATR,ACGT,TGCA,AATT,CCTC,GAGG,TTAA,ASST,TCGA                                         6                                                                                                                                                                                                                                                                                                        ,                                                          
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               	                                                	                                                     	      '                            *         	                                                                                  -                           	            	                                             D          
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         &         
                        6   5                                    -                           .   	         !         
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                                                                                                                                                                                                                                                             	                	                   	  '          *   	                              -           	    	               D    
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luciferase&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="protein_id"><V text="&lt;html&gt;&lt;body&gt;&lt;br&gt;&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="ASKVYDPEQRKRMITGPQWWARCKQMNVLDSFINYYDSEKHAENAVIFLHGNAASSYLWRHVVPHIEPVARCIIPDLIGMGKSGKSGNGSYRLLDHYKYLTAWFELLNLPKKIIFVGHDWGACLAFHYSYEHQDKIKAIVHAESVVDVIESWDEWPDIEEDIALIKSEEGEKMVLENNFFVETMLPSKIMRKLEPEEFAAYLEPFKEKGEVRRPTLSWPREIPLVKGGKPDVVQIVRNYNAYLRASDDLPKMFIESDPGFFSNAIVEGAKKFPNTEFVKVKGLHFSQEDAPDEMGKYIKSFVERVLKNEQ"/></Q></Feature><Feature recentID="16" name="SV40 poly(A) signal" type="polyA_signal" swappedSegmentNumbering="1" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="9011-9145" color="#a6acb3" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;SV40 polyadenylation signal&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="17" name="chimeric intron" type="intron" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="4205-4337" color="noColor" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;chimera between introns from human&amp;nbsp;Î²-globin and immunoglobulin heavy chain genes&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="18" name="LTR" type="LTR" swappedSegmentNumbering="1" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="10226-10695" color="#ffe4c4" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;long terminal repeat from Moloney murine leukemia virus&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="19" name="MMLV Î¨" type="misc_feature" swappedSegmentNumbering="1" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="9804-10161" color="#ffe4c4" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;packaging signal of Moloney murine leukemia virus (MMLV)&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="20" name="GCN4_v4" directionality="1" translationMW="2313.69" type="CDS" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1" maxRunOn="7481" maxFusedRunOn="7481" detectionMode="exactProteinMatch"><Segment range="4479-4535" color="#cc99b2" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="product"><V text="&lt;html&gt;&lt;body&gt;GCN4 peptide optimized to improve solubility while preserving binding to an scFv-GFP fusion protein (&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot; 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title=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot;&gt;Tanenbaum et al., 2014&lt;/a&gt;)&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="EELLSKNYHLENEVARLKK"/></Q></Feature><Feature recentID="35" name="GCN4_v4" directionality="1" translationMW="2313.69" type="CDS" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1" maxRunOn="7481" maxFusedRunOn="7481" detectionMode="exactProteinMatch"><Segment range="5559-5615" color="#cc99b2" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="product"><V text="&lt;html&gt;&lt;body&gt;GCN4 peptide optimized to improve solubility while preserving binding to an scFv-GFP fusion protein (&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot; title=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot;&gt;Tanenbaum et al., 2014&lt;/a&gt;)&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="EELLSKNYHLENEVARLKK"/></Q></Feature><Feature recentID="36" name="GCN4_v4" directionality="1" translationMW="2313.69" type="CDS" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1" maxRunOn="7481" maxFusedRunOn="7481" detectionMode="exactProteinMatch"><Segment range="5631-5687" color="#cc99b2" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="product"><V text="&lt;html&gt;&lt;body&gt;GCN4 peptide optimized to improve solubility while preserving binding to an scFv-GFP fusion protein (&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot; title=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot;&gt;Tanenbaum et al., 2014&lt;/a&gt;)&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="EELLSKNYHLENEVARLKK"/></Q></Feature><Feature recentID="37" name="GCN4_v4" directionality="1" translationMW="2313.69" type="CDS" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1" maxRunOn="7481" maxFusedRunOn="7481" detectionMode="exactProteinMatch"><Segment range="5703-5759" color="#cc99b2" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="product"><V text="&lt;html&gt;&lt;body&gt;GCN4 peptide optimized to improve solubility while preserving binding to an scFv-GFP fusion protein (&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot; title=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot;&gt;Tanenbaum et al., 2014&lt;/a&gt;)&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="EELLSKNYHLENEVARLKK"/></Q></Feature><Feature recentID="38" name="GCN4_v4" directionality="1" translationMW="2313.69" type="CDS" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1" maxRunOn="7481" maxFusedRunOn="7481" detectionMode="exactProteinMatch"><Segment range="5775-5831" color="#cc99b2" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="product"><V text="&lt;html&gt;&lt;body&gt;GCN4 peptide optimized to improve solubility while preserving binding to an scFv-GFP fusion protein (&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot; title=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot;&gt;Tanenbaum et al., 2014&lt;/a&gt;)&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="EELLSKNYHLENEVARLKK"/></Q></Feature><Feature recentID="39" name="GCN4_v4" directionality="1" translationMW="2313.69" type="CDS" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1" maxRunOn="7481" maxFusedRunOn="7481" detectionMode="exactProteinMatch"><Segment range="5847-5903" color="#cc99b2" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="product"><V text="&lt;html&gt;&lt;body&gt;GCN4 peptide optimized to improve solubility while preserving binding to an scFv-GFP fusion protein (&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot; title=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot;&gt;Tanenbaum et al., 2014&lt;/a&gt;)&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="EELLSKNYHLENEVARLKK"/></Q></Feature><Feature recentID="40" name="GCN4_v4" directionality="1" translationMW="2313.69" type="CDS" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1" maxRunOn="7481" maxFusedRunOn="7481" detectionMode="exactProteinMatch"><Segment range="5919-5975" color="#cc99b2" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="product"><V text="&lt;html&gt;&lt;body&gt;GCN4 peptide optimized to improve solubility while preserving binding to an scFv-GFP fusion protein (&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot; title=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot;&gt;Tanenbaum et al., 2014&lt;/a&gt;)&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="EELLSKNYHLENEVARLKK"/></Q></Feature><Feature recentID="41" name="GCN4_v4" directionality="1" translationMW="2313.69" type="CDS" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1" maxRunOn="7481" maxFusedRunOn="7481" detectionMode="exactProteinMatch"><Segment range="5991-6047" color="#cc99b2" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="product"><V text="&lt;html&gt;&lt;body&gt;GCN4 peptide optimized to improve solubility while preserving binding to an scFv-GFP fusion protein (&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot; title=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot;&gt;Tanenbaum et al., 2014&lt;/a&gt;)&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="EELLSKNYHLENEVARLKK"/></Q></Feature><Feature recentID="42" name="GCN4_v4" directionality="1" translationMW="2313.69" type="CDS" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1" maxRunOn="7481" maxFusedRunOn="7481" detectionMode="exactProteinMatch"><Segment range="6135-6191" color="#cc99b2" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="product"><V text="&lt;html&gt;&lt;body&gt;GCN4 peptide optimized to improve solubility while preserving binding to an scFv-GFP fusion protein (&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot; title=&quot;http://www.ncbi.nlm.nih.gov/pubmed/25307933&quot;&gt;Tanenbaum et al., 2014&lt;/a&gt;)&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="EELLSKNYHLENEVARLKK"/></Q></Feature><Feature recentID="43" name="M13 fwd" directionality="1" type="primer_bind" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="2612-2628" color="#a020f0" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;common sequencing primer, one of multiple similar variants&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="44" name="M13 rev" directionality="2" type="primer_bind" swappedSegmentNumbering="1" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="12-28" color="#a020f0" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;common sequencing primer, one of multiple similar variants&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="45" name="FRT" directionality="2" type="protein_bind" swappedSegmentNumbering="1" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="3710-3757" color="#31849b" type="standard"/><Q name="bound_moiety"><V text="&lt;html&gt;&lt;body&gt;FLP recombinase from the &lt;i&gt;Saccharomyces cerevisiae&lt;/i&gt; 2Î¼ plasmid&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="note"><V text="&lt;html&gt;&lt;body&gt;FLP-mediated recombination occurs in the 8-bp core sequence TCTAGAAA (&lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/21891781&quot; title=&quot;http://www.ncbi.nlm.nih.gov/pubmed/21891781&quot;&gt;Turan and Bode, 2011&lt;/a&gt;).&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="46" name="DD" directionality="1" translationMW="11886.90" type="CDS" allowSegmentOverlaps="0" consecutiveTranslationNumbering="0" maxRunOn="7481" maxFusedRunOn="7481"><Segment range="7155-7157" color="#993366" type="standard" translated="1" translationNumberingStartsFrom="0"/><Segment range="7158-7478" color="#993366" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="note"><V text="&lt;html&gt;&lt;body&gt;L106P mutant of FKBP12&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="product"><V text="&lt;html&gt;&lt;body&gt;destabilization domain that can be stabilized by Shield1 in the ProteoTunerâ„¢ system&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="M,GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKVDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKPE"/></Q></Feature></Features>
  J<?xml version="1.0"?><Primers nextValidID="14"><HybridizationParams minContinuousMatchLen="10" allowMismatch="1" minMeltingTemperature="40"/><Primer recentID="0" name="Amp-R" sequence="ATAATACCGCGCCACATAGC" description="Ampicillin resistance gene, reverse primer"><BindingSite location="1795-1814" boundStrand="0" annealedBases="ATAATACCGCGCCACATAGC" meltingTemperature="58"><Component hybridizedRange="1795-1814" bases="ATAATACCGCGCCACATAGC"/></BindingSite><BindingSite simplified="1" location="1795-1814" boundStrand="0" annealedBases="ATAATACCGCGCCACATAGC" meltingTemperature="58"><Component hybridizedRange="1795-1814" bases="ATAATACCGCGCCACATAGC"/></BindingSite></Primer><Primer recentID="1" name="L4440" sequence="AGCGAGTCAGTGAGCGAG" description="L4440 vector, forward primer"><BindingSite location="242-259" boundStrand="1" annealedBases="AGCGAGTCAGTGAGCGAG" meltingTemperature="58"><Component hybridizedRange="242-259" bases="AGCGAGTCAGTGAGCGAG"/></BindingSite><BindingSite simplified="1" location="242-259" boundStrand="1" annealedBases="AGCGAGTCAGTGAGCGAG" meltingTemperature="58"><Component hybridizedRange="242-259" bases="AGCGAGTCAGTGAGCGAG"/></BindingSite></Primer><Primer recentID="2" name="M13 Forward" sequence="TGTAAAACGACGGCCAGT" description="In lacZ gene. Also called M13-F20 or M13 (-21) Forward"><BindingSite location="2610-2627" boundStrand="0" annealedBases="TGTAAAACGACGGCCAGT" meltingTemperature="57"><Component hybridizedRange="2610-2627" bases="TGTAAAACGACGGCCAGT"/></BindingSite><BindingSite simplified="1" location="2610-2627" boundStrand="0" annealedBases="TGTAAAACGACGGCCAGT" meltingTemperature="57"><Component hybridizedRange="2610-2627" bases="TGTAAAACGACGGCCAGT"/></BindingSite></Primer><Primer recentID="3" name="M13 Reverse" sequence="CAGGAAACAGCTATGAC" description="In lacZ gene. Also called M13-rev"><BindingSite location="11-27" boundStrand="1" annealedBases="CAGGAAACAGCTATGAC" meltingTemperature="49"><Component hybridizedRange="11-27" bases="CAGGAAACAGCTATGAC"/></BindingSite><BindingSite simplified="1" location="11-27" boundStrand="1" annealedBases="CAGGAAACAGCTATGAC" meltingTemperature="49"><Component hybridizedRange="11-27" bases="CAGGAAACAGCTATGAC"/></BindingSite></Primer><Primer recentID="4" name="M13/pUC Forward" sequence="CCCAGTCACGACGTTGTAAAACG" description="In lacZ gene"><BindingSite location="2596-2618" boundStrand="0" annealedBases="CCCAGTCACGACGTTGTAAAACG" meltingTemperature="61"><Component hybridizedRange="2596-2618" bases="CCCAGTCACGACGTTGTAAAACG"/></BindingSite><BindingSite simplified="1" location="2596-2618" boundStrand="0" annealedBases="CCCAGTCACGACGTTGTAAAACG" meltingTemperature="61"><Component hybridizedRange="2596-2618" bases="CCCAGTCACGACGTTGTAAAACG"/></BindingSite></Primer><Primer recentID="5" name="M13/pUC Reverse" sequence="AGCGGATAACAATTTCACACAGG" description="In lacZ gene"><BindingSite location="24-46" boundStrand="1" annealedBases="AGCGGATAACAATTTCACACAGG" meltingTemperature="58"><Component hybridizedRange="24-46" bases="AGCGGATAACAATTTCACACAGG"/></BindingSite><BindingSite simplified="1" location="24-46" boundStrand="1" annealedBases="AGCGGATAACAATTTCACACAGG" meltingTemperature="58"><Component hybridizedRange="24-46" bases="AGCGGATAACAATTTCACACAGG"/></BindingSite></Primer><Primer recentID="6" name="pBABE 5'" sequence="CTTTATCCAGCCCTCAC" description="Psi packaging signal, forward primer for pBABE vectors"><BindingSite location="9338-9354" boundStrand="1" annealedBases="CTTTATCCAGCCCTCAC" meltingTemperature="51"><Component hybridizedRange="9338-9354" bases="CTTTATCCAGCCCTCAC"/></BindingSite><BindingSite simplified="1" location="9338-9354" boundStrand="1" annealedBases="CTTTATCCAGCCCTCAC" meltingTemperature="51"><Component hybridizedRange="9338-9354" bases="CTTTATCCAGCCCTCAC"/></BindingSite></Primer><Primer recentID="7" name="pBR322ori-F" sequence="GGGAAACGCCTGGTATCTTT" description="pBR322 origin, forward primer"><BindingSite location="493-512" boundStrand="1" annealedBases="GGGAAACGCCTGGTATCTTT" meltingTemperature="56"><Component hybridizedRange="493-512" bases="GGGAAACGCCTGGTATCTTT"/></BindingSite><BindingSite simplified="1" location="493-512" boundStrand="1" annealedBases="GGGAAACGCCTGGTATCTTT" meltingTemperature="56"><Component hybridizedRange="493-512" bases="GGGAAACGCCTGGTATCTTT"/></BindingSite></Primer><Primer recentID="8" name="pBRforEco" sequence="AATAGGCGTATCACGAGGC" description="pBR322 vectors, upsteam of EcoRI site, forward primer"><BindingSite location="2205-2223" boundStrand="0" annealedBases="AATAGGCGTATCACGAGGC" meltingTemperature="57"><Component hybridizedRange="2205-2223" bases="AATAGGCGTATCACGAGGC"/></BindingSite><BindingSite simplified="1" location="2205-2223" boundStrand="0" annealedBases="AATAGGCGTATCACGAGGC" meltingTemperature="57"><Component hybridizedRange="2205-2223" bases="AATAGGCGTATCACGAGGC"/></BindingSite></Primer><Primer recentID="9" name="pGEX 3'" sequence="CCGGGAGCTGCATGTGTCAGAGG" description="pGEX vectors, reverse primer"><BindingSite location="2261-2283" boundStrand="1" annealedBases="CCGGGAGCTGCATGTGTCAGAGG" meltingTemperature="66"><Component hybridizedRange="2261-2283" bases="CCGGGAGCTGCATGTGTCAGAGG"/></BindingSite><BindingSite simplified="1" location="2261-2283" boundStrand="1" annealedBases="CCGGGAGCTGCATGTGTCAGAGG" meltingTemperature="66"><Component hybridizedRange="2261-2283" bases="CCGGGAGCTGCATGTGTCAGAGG"/></BindingSite></Primer><Primer recentID="10" name="pLXSN 5'" sequence="CCCTTGAACCTCCTCGTTCGACC" description="Murine stem cell virus, forward primer. Also called MSCV"><BindingSite location="9370-9392" boundStrand="1" annealedBases="CCCTTGAACCTCCTCGTTCGACC" meltingTemperature="62"><Component hybridizedRange="9370-9392" bases="CCCTTGAACCTCCTCGTTCGACC"/></BindingSite><BindingSite simplified="1" location="9370-9392" boundStrand="1" annealedBases="CCCTTGAACCTCCTCGTTCGACC" meltingTemperature="62"><Component hybridizedRange="9370-9392" bases="CCCTTGAACCTCCTCGTTCGACC"/></BindingSite></Primer><Primer recentID="11" name="pMT2-F" sequence="TTGCCTTTCTCTCCACAGGT" description="Synthetic intron, forward primer"><BindingSite location="4319-4338" boundStrand="0" annealedBases="TTGCCTTTCTCTCCACAGGT" meltingTemperature="58"><Component hybridizedRange="4319-4338" bases="TTGCCTTTCTCTCCACAGGT"/></BindingSite><BindingSite location="6393-6402" boundStrand="1" annealedBases="CTCCACAGGT" meltingTemperature="37"><Component bases="TTGCCTTTCT"/><Component hybridizedRange="6393-6402" bases="CTCCACAGGT"/></BindingSite><BindingSite simplified="1" location="4319-4338" boundStrand="0" annealedBases="TTGCCTTTCTCTCCACAGGT" meltingTemperature="58"><Component hybridizedRange="4319-4338" bases="TTGCCTTTCTCTCCACAGGT"/></BindingSite><BindingSite simplified="1" location="6393-6402" boundStrand="1" annealedBases="CTCCACAGGT" meltingTemperature="37"><Component bases="TTGCCTTTCT"/><Component hybridizedRange="6393-6402" bases="CTCCACAGGT"/></BindingSite></Primer><Primer recentID="12" name="pRS-marker" sequence="CGGCATCAGAGCAGATTGTA" description="pRS vectors, use to sequence yeast selectable marker"><BindingSite location="2383-2402" boundStrand="0" annealedBases="CGGCATCAGAGCAGATTGTA" meltingTemperature="54"><Component hybridizedRange="2383-2402" bases="CGGCATCAGAGCAGATTGTA"/></BindingSite><BindingSite simplified="1" location="2383-2402" boundStrand="0" annealedBases="CGGCATCAGAGCAGATTGTA" meltingTemperature="54"><Component hybridizedRange="2383-2402" bases="CGGCATCAGAGCAGATTGTA"/></BindingSite></Primer><Primer recentID="13" name="SV40pA-R" sequence="GAAATTTGTGATGCTATTGC" description="SV40 polyA, reverse primer"><BindingSite location="9088-9107" boundStrand="0" annealedBases="GAAATTTGTGATGCTATTGC" meltingTemperature="51"><Component hybridizedRange="9088-9107" bases="GAAATTTGTGATGCTATTGC"/></BindingSite><BindingSite simplified="1" location="9088-9107" boundStrand="0" annealedBases="GAAATTTGTGATGCTATTGC" meltingTemperature="51"><Component hybridizedRange="9088-9107" bases="GAAATTTGTGATGCTATTGC"/></BindingSite></Primer></Primers>
  Ã<Notes>
<UUID>7519a4eb-78ca-4e5e-b9ea-f238376d967d</UUID>
<Type>Synthetic</Type>
<ConfirmedExperimentally>0</ConfirmedExperimentally>
<CustomMapLabel>SL-SunTag</CustomMapLabel>
<UseCustomMapLabel>1</UseCustomMapLabel>
<Description>The SunTag-Renilla-MS2 reporter containing cap-proximal GC-rich stem-loop.</Description>
<Created UTC="15:57:48">2023.3.15</Created>
<LastModified UTC="15:57:48">2023.3.15</LastModified>
<SequenceClass>UNA</SequenceClass>
<TransformedInto>unspecified</TransformedInto>
<References>
<Reference type="Journal Article" journal="Unpublished" journalName="Unpublished" title="Single-molecule imaging reveals translation-dependent destabilization of mRNAs"/>
</References>
</Notes>
  Y     –         
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   )<?xml version="1.0"?><CustomEnzymeSets/>
